Dr. Kelly Casperson's Substack

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Muscles and Erections

It’s More Connected Than You Think

Kelly Casperson, MD's avatar
Kelly Casperson, MD
Jul 27, 2025
∙ Paid

What if erectile dysfunction isn’t just a blood flow problem—or a hormone problem—but also a muscle problem?

That’s the question tackled in a new review by Duan, Hernandez, Lyon, Khera and colleagues in Sexual Medicine Reviews (2025), exploring the overlooked but powerful link between skeletal muscle health and male sexual function.

Spoiler: It’s not just about testosterone.

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